The European Bronchiectasis Registry (EMBARC) is a multidisciplinary research network advancing knowledge across the full spectrum of bronchiectasis. As of 2025, it has collected data from over 20,000 patients in more than 30 countries, forming one of the largest real-world bronchiectasis datasets globally. This infrastructure supports international research and clinical trials, with AI-based imaging increasingly enabling deeper disease phenotyping and mechanistic insights.
Within the project, Thirona performed automated AI-based analysis of thoracic CT scans using LungQ® Bronchus–Artery (BA) and LungQ® Mucus Plug (MP), providing quantitative evidence for:
Revealing substantial variation in both structural changes and their extent within individual patients and across different patient cohorts, the analyses demonstrated ‘substantial’ intra- and inter-patient heterogeneity.
Integrated with patient-level registry data, these imaging biomarkers support longitudinal assessment, contributing to deeper phenotyping, and improved disease stratification within the EMBARC registry.
