AI-driven CT quantification of mucus plugs to evaluate the effect of inhaled hypertonic saline in children aged 3-6 years with cystic fibrosis
Clinical benefit without sweat chloride response after ETI therapy in an adult with cystic fibrosis bearing the L467F; F508del complex CFTR allele: a case report and the role of AIassisted chest CT in longitudinal monitoring
Bronchial segmental heterogeneity of responsiveness to modulator therapy in cystic fibrosis: linking structural improvements on computed tomography to inflammation in bronchoalveolar lavage fluid
Impact of two years of treatment with ETI on longitudinal changes in structural lung disease in people with Cystic Fibrosis
Correlation Between Segmental Bronchial Wall Thickness and Bronchoalveolar Lavage Markers of Inflammation and Mucus Before and After Elexacaftor-Tezacaftor-Ivacaftor Therapy
Quantitative CT Analysis for Monitoring Mycobacteriophage Therapy in a Cystic-Fibrosis Patient With a Mycobacterium Abscessus Pulmonary Infection
Progression of structural lung disease and lung function in adolescents with cystic fibrosis
Structural lung abnormalities in children and adults with cystic fibrosis after ETI using AI automated algorithm
AI-based mucus plug analysis to evaluate the effect of inhaled hypertonic saline in preschool children with CF: a randomized controlled trial
Investigating imaging markers in cystic fibrosis preschoolers using manual and automated algorithms
The effect of Elexacaftor/Tezacaftor/Ivacaftor (ETI) on bronchial tapering as marker of bronchial dilatation in people with CF aged 12 above (RECOVER study)
10 years partnership for solving COPD imaging challenges

Prof. David Lynch
A decade of AI-enabled lung imaging

Prof. Bram van Ginneken
Evaluation of QCT metrics for COPD phenotyping in the COPDGene cohort

Building on over a decade of pioneering research from the COPDGene project, this ancillary study is designed to further advance the understanding of chronic obstructive pulmonary disease (COPD) through artificial intelligence–driven imaging biomarkers. Specifically, the study will validate a selected set of AI-based quantitative CT (QCT) measurements and evaluate their associations with disease exacerbations and […]
Effect of elexacaftor–tezacaftor–ivacaftor on bronchial dilatations in adolescents with cystic fibrosis: a multicentre prospective observational study
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation
Validation of an artificial intelligence-based automated PRAGMA and mucus plugging algorithm in pediatric cystic fibrosis
Renewed ISO 13485 and MDR Approvals, and our 1st MDSAP Certification

We are proud to announce that Thirona has successfully renewed its ISO 13485 and EU MDR certifications and, for the first time, achieved certification under the Medical Device Single Audit Program (MDSAP) – a major milestone in strengthening our global regulatory foundation. The ISO 13485 certification, an internationally recognized standard for quality management systems (QMS) […]